CALL FOR PAPERS Stem Cell Physiology and Pathophysiology Nitric oxide induces cancer stem cell-like phenotypes in human lung cancer cells
نویسندگان
چکیده
Nuttida Yongsanguanchai, Varisa Pongrakhananon, Apiwat Mutirangura, Yon Rojanasakul, and Pithi Chanvorachote Pharmaceutical Technology (International) Program, Chulalongkorn University, Bangkok, Thailand; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand; CellBased Drug and Health Products Development Research Unit, Chulalongkorn University, Bangkok, Thailand; Center of Excellence in Molecular Genetics of Cancer and Human Diseases, Department of Anatomy, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; School of Pharmacy, West Virginia University, Morgantown, West Virginia
منابع مشابه
A Glance into Cancer Stem Cells
The presence of stem cells in leukemia and solid tumors has been demonstrated in recent decades. Cancer stem cells have the potency of tumorigenesis; furthermore, they have the ability of self-renewing and differentiation like other stem cells. They also play important role in the process of tumor invasion and metastasis. Several studies have been performed to discover the spe...
متن کاملNitric oxide induces cancer stem cell-like phenotypes in human lung cancer cells.
Even though tremendous advances have been made in the treatment of cancers during the past decades, the success rate among patients with cancer is still dismal, largely because of problems associated with chemo/radioresistance and relapse. Emerging evidence has indicated that cancer stem cells (CSCs) are behind the resistance and recurrence problems, but our understanding of their regulation is...
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Background & Aims: Mesenchymal stem cells (MSCs) are non-hematopoietic multipotant cells, which multiply through attaching to culture plates. Toll-like receptors (TLRs) are inherent immune sensors and regulators of immunomodulatory activities of MSCs. The aim of this study was to investigate the effects of zymosan on stem cell polarization into anti-inflammatory phenotypes through the productio...
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Halophilic archaea are known as the novel producers of natural products and their supernatant metabolites could have cytotoxic effects on cancer cells. In the present study, we screened the anticancer potential of supernatant metabolites from eight native haloarchaeal strains obtained from a culture collection in Iran. Five human cancer cell lines including breast, lung, prostate and also human...
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